界*實(shí)驗(yàn)材料供應(yīng)商 Solulink正式授權(quán)上海起發(fā)為其中國代理， Solulink在一直是行業(yè)的*,一直為廣大科研客戶提供zui為的產(chǎn)品和服務(wù),上海起發(fā)一直秉承為中國科研客戶帶來的產(chǎn)品，的服務(wù)，簽約 Solulink就是為了給廣大科研客戶帶來更加完善的產(chǎn)品和服務(wù),您的滿意將是我們zui大的收獲

 Solulink中國代理, Solulink上海代理， Solulink北京代理，Solulink廣東代理， Solulink江蘇代理Solulink湖北代理,Solulink天津,Solulink黑龍江代理,Solulink內(nèi)蒙古代理,Solulink吉林代理,Solulink福建代理, Solulink江蘇代理, Solulink浙江代理, Solulink四川代理,

Solulink — 生物分子標(biāo)記的 
Solulink公司致力于發(fā)展高性能的生物分子連接產(chǎn)品，他們不斷的努力幫助您保持在生物科學(xué)研究的zui前沿。可用于任何含有氨基的生物分子標(biāo)記的ChromaLink™抗體標(biāo)簽試劑盒  （ChromaLink™ Antibody Labeling Kit），和One-Shot（單標(biāo)簽）系列試劑盒的成功開發(fā)代表著他們始終如一地提供創(chuàng)新產(chǎn)品的承諾，以滿足客戶不斷變化的需求。 
Solulink是*家提供包括純化的完整抗體標(biāo)記試劑盒的公司，并且正在開發(fā)更多令人振奮的新結(jié)合試劑盒。這一切都基于一個(gè)成功的產(chǎn)品理念：易于使用，價(jià)格便宜。 
Solulink公司的產(chǎn)品包括：抗體標(biāo)簽、抗體-寡肽標(biāo)簽、生物素標(biāo)簽、磁珠及瓊脂糖等。

S‐HyNic

C13H14N4O4 MW 290.27 

相關(guān)產(chǎn)品如下：

Introduction to SoluLinK Bioconjugation Technology

SoluLinK’s core technology is based on the formation of a stable bis‐arylhydrazone formed from an aromatic hydrazine and an aromatic aldehyde.  S‐HyNic 1 (succinimidyl 6‐hydrazinonicotinate acetone hydrazone, SANH) is used to incorporate aromatic hydrazine moieties on biomolecules.  S‐HyNic is an amino‐reactive reagent that directly converts amino groups on biomolecules and surfaces to HyNic groups.  S‐ 4FB 2 (succinimidyl 4‐formylbenzoate, SFB) is used to convert amino groups to aromatic aldehydes (4‐formylbenzamide (4FB) groups).   Addition of a HyNic‐modified biomolecule to a 4FB‐modified biomolecule or surface directly leads to the formation of the conjugate (Figure 1).  The bis‐arylhydrazone bond is stable to 92O C and pH 2.0‐10.0.    The recommended pH for antibody conjugation is 6.0.    Unlike thiol‐based conjugation protocols where reducing reagents are required that that can compromise the activity of proteins by cleaving disulfide bonds, the HyNic‐4FB conjugation couple leaves disulfide bonds intact. No oxidants, reductants or metals are required in the preparation of conjugate.    Further enhancing the many advantages of the HyNic/4FB conjugation couple is the discovery by Dirksen et al.1 that showed that aniline catalyzes the formation of this Schiff’s base.    This is especially effective for large biomolecule conjugations.    In the case of antibody‐protein conjugations the addition of 10 mM aniline to the reaction mixture converts >95% of the antibody to conjugate in ~2 hours using 1‐2 mole equivalents of second protein. The HyNic‐4FB conjugation couple is chromophoric‐  the conjugate bond absorbs at 354 nm and has a molar extinction coefficient of 29000.    This allows (1) real time spectrophotometric monitoring of a conjugate reaction, (2) ability to ‘visualize’ the conjugate during chromatographic purification using a UV or photodiode array detector and (3) quantification of conjugation.  Furthermore, the level of incorporation of HyNic groups can be quantified colorimetrically as reaction with 2‐ sulfobenzaldehyde (SoluLinK catalog# # S‐2005‐100) yields a chromophoric product that absorbs at A350 with a molar extinction coefficient of 20000 (Figure 2).  Links to procedures and calculators to guide users through this process are given in the procedures below.   S‐HyNic (Solulink catalog: S‐1004‐105 (5 X 1.0 mg) and S‐1004‐010 (25 mg)) is an NHS ester that converts amines on biomolecules and surfaces to HyNic moieties for conjugation to 4FB‐modified biomolecules. 

我們公司zui大優(yōu)勢(shì)是強(qiáng)大的采購，

1：基本什么都能進(jìn)口，血清，抗體，耗材，還有部分限制進(jìn)口的，

2：貨品全，現(xiàn)經(jīng)營過700多個(gè)品牌，基本所有生物試劑耗材都可以進(jìn)口，特別是冷偏的產(chǎn)品那就更有優(yōu)勢(shì)，

3：提供加急服務(wù)，一般1-2周到貨，超過時(shí)限加急費(fèi)全免

4：價(jià)格公道，絕大部分價(jià)格有優(yōu)勢(shì)，當(dāng)然不能保證100%產(chǎn)品都是,因?yàn)橐馕吨鴽]有服務(wù).

5：良好的信譽(yù)，大部分客戶我們提供貨到付款服務(wù)，客戶包括清華，北大 交大 復(fù)旦，中山等100多所大學(xué)，ROCHE，阿斯利康，國藥 ，fisher等500多家公司

6：我們*代理的品牌有：Antibody Research Corporation，arcticzymes，Biorelevant，AmberGen, Inc. ，clemente-associates，clodronaiposomes，Columbia Biosciences，enzyme research，Gene Bridges GmbH，Genovis，AmberGen, Inc.  Biotechnology GmbH，Haematologic Technologies HTI Haemtech，hookelabs，Immudex，Innovative Research of America，inspiralis ，List Biological Laboratories, Inc.，lumafluor，Microsurfaces，multiplicom，nanotools，Pel-Freez Biologicals，pentapharm，progen，Protein Ark，QA-Bio,Inc，QA-Bio,IncQuickZyme Biosciences，Teknova，TriLink BioTechnologies, Inc.，Zyagen Laboratories 等

7：我們還是invitrogen,qiagen,Midland BioProducts Corporationam,sigma;neb,roche,merck, rnd,BD, GE,pierce,BioLegend等知名*批發(fā)，歡迎合作。